Changes in Gene Expression Patterns in the Tumor Microenvironment of Head and Neck Squamous Cell Carcinoma Under Chemoradiotherapy Depend on Response

Chemoradiotherapy (CRT) is a standard treatment for advanced head and neck squamous cell carcinoma (HNSCC).Unfortunately, not all patients respond to this therapy and require further treatment, either salvage surgery or palliative therapy.The addition of immunotherapy to CRT is currently being investigated and early results describe a mixed respons

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Functional nature of the spasmolytic effect, phytochemical composition and acute toxicity studies on Sauromatum guttatum

The aim of the present work was to study the functional nature of the potential spasmolytic effect of the crude extract of Sauromatum guttaum.It was found positive for the presence of alkaloid and tannins.In isolated rabbit jejunum preparation, S.guttaum caused inhibition of spontaneous and high K+ (80 mM)-induced contractions, with respective EC50

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Design of a Novel Protection Device of Mine-used Diesel Locomotive

For problems of single function and poor function-expanding caused by centralized control mode of current protection device of mine-used diesel locomotive, the paper put forward a design scheme of novel protection device of mine-used diesel locomotive based on CAN bus and introduced software and hardware designs of the protection device 3 Piece Pow

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